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J. M. Reinhardt, N. D. D'Souza, and E. A. Hoffman. Accurate Measurement of Intra-Thoracic Airways. IEEE Trans. Medical Imaging, vol. 16, no. 6, pp. 820-827, 1997.

Abstract: Airway geometry measurements can provide information regarding pulmonary physiology and pathophysiology. There has been considerable interest in measuring intra-thoracic airways in two-dimensional slices from volumetric X-ray CT. Such measurements can be used to evaluate and track the progression of diseases affecting the airways. A popular airway measurement method uses the ?half-max? criteria, in which the gray level at the airway wall is estimated to be halfway between the minimum and maximum gray levels along a ray crossing the edge. However, because the scanning process introduces blurring, the half-max approach may not be applicable across all airway sizes. We propose a new measurement method based on a model of the scanning process. In our approach, we examine the gray-level profile of a ray crossing the airway wall and use a maximum-likelihood method to estimate the airway inner and outer radius. Using CT scans of a physical phantom, we present results showing that the new approach is more accurate than the half-max method at estimating wall location for thin-walled airways.

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Keywords: airways measurement

Other publications by: J. M. Reinhardt, N. D. D'Souza, E. A. Hoffman

Related journal papers:

O. Saba, E. A. Hoffman, and J. M. Reinhardt. Maximizing Quantitative Accuracy of Lung Airway Lumen and Wall Measures Obtained from X-ray CT Imaging. J. Applied Physiology, vol. 95, pp. 1063-1095, 2003. (details)
T. E. Robinson, F. R. Long, P. Raman, P. Saha, M. J. Edmond, J. M. Reinhardt, R. Raman, and A. S. Brody. An airway phantom to standardize CT acquisition in multi-center clinical trials. Acad. Radiol., vol. 16, no. 9, pp. 1134-1141, 2009. (details)
C. P. Rooney, M. Suter, G. McLennan, M. Donnelley, J. M. Reinhardt, A. Delsing, E. A. Hoffman, and J. Zabner. Laser Fluorescence Bronchoscopy for Detection of Fluorescent Reporter Genes in Airway Epithelia. Gene Therapy, vol. 9, no. 23, pp. 1639-1644, 2002. (details)
D. Aykac, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. Segmentation and analysis of the human airway tree from three-dimensional X-Ray CT images. IEEE Trans. Medical Imaging, vol. 22, no. 8, pp. 940-950, 2003. (details)
M. Suter, J. Tschirren, J. M. Reinhardt, M. Sonka, E. A. Hoffman, W. E. Higgins, and G. McLennan. Evaluation of the human airway with multi-detector X-ray computed tomography and optical imaging. Physiological Measurement, vol. 25, no. 4, pp. 837-847, 2004. (details)

Related conference papers:

N. D. D'Souza, J. M. Reinhardt, and E. A. Hoffman. ASAP: Interactive Quantification of 2D Airway Geometry. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 2709, pp. 180-196, Newport Beach, CA, 1996. (details)
R. A. Chiplunkar, J. M. Reinhardt, and E. A. Hoffman. Segmentation and Quantification of the Primary Human Airway Tree from 3-D X-ray CT. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 403-414, Newport Beach, CA, 1997. (details)
J. M. Reinhardt, S. A. Raab, N. D. D'Souza, and E. A. Hoffman. Intra-thoracic airway measurement: Ex vivo validation. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 69-80, Newport Beach, CA, 1997. (details)
J. M. Reinhardt, W. Park, E. A. Hoffman, and M. Sonka. Intrathoracic airway wall detection using graph search with CT scanner PSF information. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 93-101, Newport Beach, CA, 1997. (details)
O. Saba, E. A. Hoffman, and J. M. Reinhardt. Computed tomographic-based estimation of airway size with correction for scanned plane tilt angle. In C.-T. Chen and A. V. Clough, eds., Proc. SPIE Conf. Medical Imaging, vol. 3978, pp. 58-66, San Diego, CA, 2000. (details)

Related theses:

O. Saba. Accurate estimation of airway geometry with tilt angle estimation from 2D HRCT slices. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
D. Aykac. Segmentation and analysis of the human airway tree from 3D X-ray CT images. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
D. Gopalakrishnan. Color analysis of the human airway wall. MS thesis, The University of Iowa, Iowa City, IA, 2003. (details)
P. Kellen. Computer automated image analysis of fluoroscopic swallowing studies. MS thesis, The University of Iowa, Iowa City, IA, 2008. (details)
S. V. Bodas. Improved association graph matching of intra-patient airway trees. MS thesis, The University of Iowa, Iowa City, IA, 2008. (details)