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A. Kiraly, W. E. Higgins, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. 3D human airway segmentation for virtual bronchoscopy. In A. V. Clough and C.-T. Chen, eds., Proc. SPIE Conf. Medical Imaging, vol. 4683, pp. 16-29, San Diego, CA, 2002.

Abstract: This paper describes a new airway segmentation algorithm that improves the speed of morphological-based segmentation approaches. Airway segmentation methods based on morphological operators suffer from the indiscriminant application of all operators to a large area. Using the results of three-dimensional (3D) region growing, the discrete application of larger operators is possible. This change can greatly decrease the execution time of the algorithm. This hybrid approach typically runs 5 to 10 times faster than the original algorithm. 3D adaptive region growing, morphological segmentation, and the hybrid approach are then compared via data obtained from human volunteers using a Marconi MX8000 scanner with the lungs held at 85% TLC. Results show that filtering improves robustness of these techniques. The hybrid approach allows for the practical use of morphological operators to create a clinically useful segmentation. We also demonstrate the method?s utility for peripheral nodule analysis in a human case.

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Keywords: airways bronchoscopy

Other publications by: A. Kiraly, W. E. Higgins, E. A. Hoffman, G. McLennan, J. M. Reinhardt

Related journal papers:

C. P. Rooney, M. Suter, G. McLennan, M. Donnelley, J. M. Reinhardt, A. Delsing, E. A. Hoffman, and J. Zabner. Laser Fluorescence Bronchoscopy for Detection of Fluorescent Reporter Genes in Airway Epithelia. Gene Therapy, vol. 9, no. 23, pp. 1639-1644, 2002. (details)
M. Suter, J. Tschirren, J. M. Reinhardt, M. Sonka, E. A. Hoffman, W. E. Higgins, and G. McLennan. Evaluation of the human airway with multi-detector X-ray computed tomography and optical imaging. Physiological Measurement, vol. 25, no. 4, pp. 837-847, 2004. (details)
M. Suter, J. M. Reinhardt, P. Montague, P. Taft, J. Lee, J. Zabner, and G. McLennan. Bronchoscopic imaging of the pulmonary mucosal vasculature responses to inflammatory mediators. J. Biomed. Optics, vol. 10, no. 3, pg. 34013, 2005. (details)
M. Suter, G. McLennan, J. M. Reinhardt, D. Riker, and E. A. Hoffman. Macro-optical color assessment of the pulmonary airways with subsequent three-dimensional multidetector-x-ray-computed-tomography assisted display. J. Biomed. Optics, vol. 10, no. 5, pg. 51703, 2005. (details)
M. Suter, J. M. Reinhardt, and G. McLennan. Integrated CT/bronchoscopy in the central airways: Preliminary results. Acad. Radiol., vol. 15, no. 6, pp. 786-798, 2008. (details)

Related conference papers:

R. D. Swift, W. E. Higgins, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. Automatic axis generation for 3D virtual-bronchoscopic image assessment. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3337, pp. 73-84, San Diego, CA, 1998. (details)
D. Gopalakrishnan, G. McLennan, M. Donnelley, A. Delsing, M. Suter, D. Flaherty, J. Zabner, E. A. Hoffman, and J. M. Reinhardt. Color bronchoscopic analysis of the human airway tree. In A. V. Clough and C.-T. Chen, eds., Proc. SPIE Conf. Medical Imaging, vol. 4683, pp. 341-351, San Diego, CA, 2002. (details)
M. Suter, J. M. Reinhardt, M. Sonka, W. E. Higgins, E. A. Hoffman, and G. McLennan. Three-dimensional true color topographical analysis of the pulmonary airways. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5369, pp. 189-198, San Diego, CA, 2004. (details)
A. Kiraly, J. M. Reinhardt, E. A. Hoffman, G. McLennan, and W. E. Higgins. Virtual bronchoscopy for quantitative airway analysis. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5746, pp. 369-383, San Diego, CA, 2005. (details)
M. Suter, J. M. Reinhardt, D. Easker, D. Riker, E. A. Hoffman, and G. McLennan. Classification of pulmonary airway disease based on mucosal color analysis. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5746, pp. 465-473, San Diego, CA, 2005. (details)

Related theses:

D. Gopalakrishnan. Color analysis of the human airway wall. MS thesis, The University of Iowa, Iowa City, IA, 2003. (details)
D. Aykac. Segmentation and analysis of the human airway tree from 3D X-ray CT images. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
O. Saba. Accurate estimation of airway geometry with tilt angle estimation from 2D HRCT slices. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
S. V. Bodas. Improved association graph matching of intra-patient airway trees. MS thesis, The University of Iowa, Iowa City, IA, 2008. (details)