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D. Gopalakrishnan, G. McLennan, M. Donnelley, A. Delsing, M. Suter, D. Flaherty, J. Zabner, E. A. Hoffman, and J. M. Reinhardt. Color bronchoscopic analysis of the human airway tree. In A. V. Clough and C.-T. Chen, eds., Proc. SPIE Conf. Medical Imaging, vol. 4683, pp. 341-351, San Diego, CA, 2002.

Abstract: A bronchoscope can be used to examine the mucosal surface of the airways for abnormalities associated with a variety of lung diseases. The diagnosis of these abnormalities through the process of bronchoscopy is based, in part, on changes in airway wall color. Therefore it is important to characterize the normal color inside the airways. We propose a standardized method to calibrate the bronchoscopic imaging system and to tabulate the normal colors of the airway. Our imaging system consists of a Pentium PC and video frame grabber, coupled with a true color bronchoscope. The calibration procedure uses 24 standard color patches. Images of these color patches at three different distances (1, 1.5, and 2 cm) were acquired using the bronchoscope in a darkened room, to assess repeatability and sensitivity to illumination. The images from the bronchoscope are in a device-dependent Red-Green-Blue (RGB) color space, which was converted to a tri-stimulus image and then into a device-independent color space sRGB image by a fixed polynomial transformation. Images were acquired from five normal human volunteer subjects, two cystic fibrosis (CF) patients and one normal heavy smoker subject. The hue and saturation values of regions within the normal airway were tabulated and these values were compared with the values obtained from regions within the airways of the CF patients and the normal heavy smoker. Repeated measurements of the same region in the airways showed no measurable change in hue or saturation.

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Keywords: airways bronchoscopy color

Other publications by: D. Gopalakrishnan, G. McLennan, M. Donnelley, A. Delsing, M. Suter, D. Flaherty, J. Zabner, E. A. Hoffman, J. M. Reinhardt

Related journal papers:

C. P. Rooney, M. Suter, G. McLennan, M. Donnelley, J. M. Reinhardt, A. Delsing, E. A. Hoffman, and J. Zabner. Laser Fluorescence Bronchoscopy for Detection of Fluorescent Reporter Genes in Airway Epithelia. Gene Therapy, vol. 9, no. 23, pp. 1639-1644, 2002. (details)
M. Suter, J. Tschirren, J. M. Reinhardt, M. Sonka, E. A. Hoffman, W. E. Higgins, and G. McLennan. Evaluation of the human airway with multi-detector X-ray computed tomography and optical imaging. Physiological Measurement, vol. 25, no. 4, pp. 837-847, 2004. (details)
M. Suter, J. M. Reinhardt, P. Montague, P. Taft, J. Lee, J. Zabner, and G. McLennan. Bronchoscopic imaging of the pulmonary mucosal vasculature responses to inflammatory mediators. J. Biomed. Optics, vol. 10, no. 3, pg. 34013, 2005. (details)
M. Suter, G. McLennan, J. M. Reinhardt, D. Riker, and E. A. Hoffman. Macro-optical color assessment of the pulmonary airways with subsequent three-dimensional multidetector-x-ray-computed-tomography assisted display. J. Biomed. Optics, vol. 10, no. 5, pg. 51703, 2005. (details)
M. Suter, J. M. Reinhardt, and G. McLennan. Integrated CT/bronchoscopy in the central airways: Preliminary results. Acad. Radiol., vol. 15, no. 6, pp. 786-798, 2008. (details)

Related conference papers:

M. Suter, J. M. Reinhardt, M. Sonka, W. E. Higgins, E. A. Hoffman, and G. McLennan. Three-dimensional true color topographical analysis of the pulmonary airways. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5369, pp. 189-198, San Diego, CA, 2004. (details)
M. Suter, J. M. Reinhardt, D. Easker, D. Riker, E. A. Hoffman, and G. McLennan. Classification of pulmonary airway disease based on mucosal color analysis. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5746, pp. 465-473, San Diego, CA, 2005. (details)
R. D. Swift, W. E. Higgins, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. Automatic axis generation for 3D virtual-bronchoscopic image assessment. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3337, pp. 73-84, San Diego, CA, 1998. (details)
A. Kiraly, W. E. Higgins, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. 3D human airway segmentation for virtual bronchoscopy. In A. V. Clough and C.-T. Chen, eds., Proc. SPIE Conf. Medical Imaging, vol. 4683, pp. 16-29, San Diego, CA, 2002. (details)
A. Kiraly, J. M. Reinhardt, E. A. Hoffman, G. McLennan, and W. E. Higgins. Virtual bronchoscopy for quantitative airway analysis. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5746, pp. 369-383, San Diego, CA, 2005. (details)

Related theses:

D. Gopalakrishnan. Color analysis of the human airway wall. MS thesis, The University of Iowa, Iowa City, IA, 2003. (details)
D. Aykac. Segmentation and analysis of the human airway tree from 3D X-ray CT images. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
O. Saba. Accurate estimation of airway geometry with tilt angle estimation from 2D HRCT slices. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
S. V. Bodas. Improved association graph matching of intra-patient airway trees. MS thesis, The University of Iowa, Iowa City, IA, 2008. (details)