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R. A. Chiplunkar, J. M. Reinhardt, and E. A. Hoffman. Segmentation and Quantification of the Primary Human Airway Tree from 3-D X-ray CT. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 403-414, Newport Beach, CA, 1997.

Abstract: There has been an increased interest in automatic segmentation of volumetric medical image data. One of the reasons is that automated segmentation takes away the variability which exists when data is segmented manually. It also reduces processing time significantly. However, because of the stochastic nature of biological structures and the fact that no two data sets and scanner models are alike, it is very important to develop automated methods which process images in an adaptive manner and use a priori information to simplify the process. The method which we present here adaptively determines thresholds in order to segment out the primary human airway tree and uses some a priori information about the manner in which branching occurs, specifically the order in which the upward and downward branches arise from the right and left bronchi. We present preliminary results from this method, which automatically segments out the first four generations of the airway tree reliably, in data sets from both normal and airway compromised subjects and present comparisons with the current ?gold standard? of manual segmentation.

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Keywords: airways measurement segmentation

Other publications by: R. A. Chiplunkar, J. M. Reinhardt, E. A. Hoffman

Related journal papers:

J. M. Reinhardt, N. D. D'Souza, and E. A. Hoffman. Accurate Measurement of Intra-Thoracic Airways. IEEE Trans. Medical Imaging, vol. 16, no. 6, pp. 820-827, 1997. (details)
D. Aykac, E. A. Hoffman, G. McLennan, and J. M. Reinhardt. Segmentation and analysis of the human airway tree from three-dimensional X-Ray CT images. IEEE Trans. Medical Imaging, vol. 22, no. 8, pp. 940-950, 2003. (details)
O. Saba, E. A. Hoffman, and J. M. Reinhardt. Maximizing Quantitative Accuracy of Lung Airway Lumen and Wall Measures Obtained from X-ray CT Imaging. J. Applied Physiology, vol. 95, pp. 1063-1095, 2003. (details)
T. E. Robinson, F. R. Long, P. Raman, P. Saha, M. J. Edmond, J. M. Reinhardt, R. Raman, and A. S. Brody. An airway phantom to standardize CT acquisition in multi-center clinical trials. Acad. Radiol., vol. 16, no. 9, pp. 1134-1141, 2009. (details)
J. M. Reinhardt and W. E. Higgins. Paradigm for Shape-Based Image Analysis. Optical Engineering, vol. 37, no. 2, pp. 570-581, 1998. (details)

Related conference papers:

J. Thiesse, J. M. Reinhardt, J. de Ryk, J. Leinen, W. Recheis, E. A. Hoffman, and G. McLennan. Three-dimensional visual truth of the normal airway tree for use as a quantitative comparison to micro-CT reconstructions. In A. Amini and A. Manduca, eds., Proc. SPIE Conf. Medical Imaging, vol. 5746, pp. 369-383, San Diego, CA, 2005. (details)
N. D. D'Souza, J. M. Reinhardt, and E. A. Hoffman. ASAP: Interactive Quantification of 2D Airway Geometry. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 2709, pp. 180-196, Newport Beach, CA, 1996. (details)
J. M. Reinhardt, S. A. Raab, N. D. D'Souza, and E. A. Hoffman. Intra-thoracic airway measurement: Ex vivo validation. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 69-80, Newport Beach, CA, 1997. (details)
J. M. Reinhardt, W. Park, E. A. Hoffman, and M. Sonka. Intrathoracic airway wall detection using graph search with CT scanner PSF information. In E. A. Hoffman, ed., Proc. SPIE Conf. Medical Imaging, vol. 3033, pp. 93-101, Newport Beach, CA, 1997. (details)
O. Saba, E. A. Hoffman, and J. M. Reinhardt. Computed tomographic-based estimation of airway size with correction for scanned plane tilt angle. In C.-T. Chen and A. V. Clough, eds., Proc. SPIE Conf. Medical Imaging, vol. 3978, pp. 58-66, San Diego, CA, 2000. (details)

Related theses:

D. Aykac. Segmentation and analysis of the human airway tree from 3D X-ray CT images. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
O. Saba. Accurate estimation of airway geometry with tilt angle estimation from 2D HRCT slices. MS thesis, The University of Iowa, Iowa City, IA, 2000. (details)
D. Gopalakrishnan. Color analysis of the human airway wall. MS thesis, The University of Iowa, Iowa City, IA, 2003. (details)
S. Ukil. Anatomy-guided lung lobe segmentation and fissure analysis in X-ray CT images. PhD thesis, The University of Iowa, Iowa City, IA, 2006. (details)
L. Zhang. Atlas-driven lung lobe segmentation in volumetric X-ray CT images. PhD thesis, The University of Iowa, Iowa City, IA, 2002. (details)